Services

• Rodent surgical and pharmacological models
  • Stroke (focal and global ischemia) models
  • Stereotaxic brain injections (for virus, tracers)
  • Brain and spinal cord traumatic injury
  • Epilepsy models and monitoring
  • Perinatal hypoxia / ischemia
  • Interface with microscopy core for in vivo imaging
• Mouse genetic models
  • Transgenic disease models of ALS, Alzheimer's, and other neurodegenerative conditions
  • Transgenic mice for scientific investigation, including GFP
  • Interface with transgenic facility and assistance with colonies
  • Lists of transgenic models, breeding
• Veterinary care resources
  • Animal survival care and facilities
  • Animal safety, protocols, ASC approvals

The overall objective of the Animal Models Core is to assist translation of scientific discoveries to rodent models and to facilitate development of new therapeutic strategies for nervous system diseases. The Animal Models Core can provide access to core equipment and facilities, and expertise for surgery or protocol development. In addition, specific surgical and genetic models of disease will be made available to the Washington University community to accelerate investigation in disease-related neuroscience.