| | Randall Bateman, M.D. Assistant Professor of NeurologyAlzheimer's disease: Pathophysiology, biomarkers, predictive diagnostics and treatments |
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| Philip V. Bayly, Ph.D. Hughes Professor of Mechanical Engineering; Professor of Biomedical EngineeringBiomechanical factors in traumatic injury to the brain and spinal cord |
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| Janice E. Brunstrom, M.D. Associate Professor of Neurology and Pediatrics; Director of the Pediatric Neurology Cerebral Palsy Center at St. Louis Children's HospitalMotor disorders arising from injury to the developing brain |
| | Guojun Bu, Ph.D. Professor of Pediatrics and Cell Biology & PhysiologyLDL receptor family members in human disease |
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| Nigel Cairns, Ph.D., MRCPath Research Associate Professor of Neurology and Pathology & Immunology; Director, Betty Martz Laboratory for Neurodegenerative ResearchProtein misfolding, inclusion formation and neurodegeneration in Frontotemporal Dementias |
| | Valeria Cavalli, Ph.D. Assistant Professor of Anatomy and NeurobiologyAxonal Transport, Injury Signaling and Nerve Regeneration |
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| Anne H. Cross, M.D. Professor of Neurology; Manny and Rosalyn Rosenthal and Dr. John Trotter MS Center Chair in Neuroimmunology; Director, Multiple Sclerosis CenterNeuroimmunology related to multiple sclerosis |
| | C. Michael Crowder, M.D., Ph.D. Associate Professor of Anesthesiology and Developmental BiologyFundamental mechanisms of neuronal cell death following hypoxic injury |
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| Hans H. Dietrich, Ph.D. Research Assistant Professor of Neurological SurgeryRegulatory mechanisms of cerebrovascular microcirculation |
| | Alex S. Evers, M.D. Henry E. Mallinckrodt Professor and Head of Anesthesiology; Professor of Internal Medicine and Developmental BiologyMolecular mechanisms of anesthetics in the nervous system |
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| Anne M. Fagan Niven, Ph.D. Research Associate Professor of NeurologyBiomarkers, and mechanisms of apoE4 action in Alzheimer's Disease |
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| | Jeffrey M. Gidday, Ph.D. Associate Professor of Neurological SurgeryEndogenous mechanisms of vascular and parenchymal protection in CNS ischemia. |
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| Alison M. Goate, D.Phil. Samuel and Mae S. Ludwig Chair in Psychiatry; Professor of Neurology and Genetics; Hope Center Steering CommitteeLinkage and association studies to uncover genetic susceptibility to neuropsychiatric disease. |
| | Mark P. Goldberg, M.D. Professor of Neurology, Neurobiology, and Biomedical Engineering; Director of the Hope Center for Neurological DisordersMechanisms of ischemic injury and recovery in white matter axons and glia. |
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| | Phyllis I. Hanson, M.D., Ph.D. Associate Professor of Cell Biology and PhysiologyProtein-protein and protein-membrane interactions in neuronal membrane trafficking. |
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| | David M. Holtzman, M.D. Andrew B. and Gretchen P. Jones Professor and Chairman of Neurology; Professor of Molecular Biology; Hope Center Steering CommitteeCellular/Molecular/Biomarkers studies of Alzheimer’s disease and neonatal brain injury. |
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| Mark Jacquin, Ph.D. Professor of NeurologyMolecular mechanisms of mammalian sensory system development, plasticity and repair. |
| | Sanjay Jain, M.D., Ph.D. Assistant Professor of Internal MedicineGFL-Ret mediated mechanisms in the development, repair and regeneration of the nervous and urogenital systems
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| Eugene M. Johnson, Ph.D. Professor of Neurology and Developmental Biology; Hope Center Steering CommitteeBiological function and pharmacological potential of GFL neurotrophic factors |
| | Robyn S. Klein, M.D., Ph.D. Assistant Professor of Internal MedicineMolecular basis of inflammation-associated dysfunction in viral and autoimmune encephalitides |
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| Raphael Kopan, Ph.D. Professor of Internal Medicine and Developmental BiologyStudies of cell fate determination in mammalian system with focus on Notch mediated signal transduction. |
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| Jin-Moo Lee, M.D., Ph.D. Associate Professor of NeurologyUnderstanding the molecular pathogenesis of spontaneous intracerebral hemorrhage |
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| | Steven J. Mennerick, Ph.D. Associate Professor of Psychiatry and Anatomy & NeurobiologyPhysiology of glutamate and GABA neurotransmission in the CNS. |
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| Jeffrey D. Milbrandt, M.D., Ph.D. David Clayson Professor of Neurology; Professor of Pathology & Immunology and Internal Medicine; Hope Center Steering CommitteeAxonal degeneration, regulation of myelination, neuronal energetics and mitochondrial function in neuropathy and neurodegenerative disease |
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| Jeanne M. Nerbonne, Ph.D. Alumni Endowed Professor of Developmental BiologyMolecular mechanisms controlling the function, expression and properties of voltage-gated K channels in cardiac and neuronal cells |
| | Karen L. O'Malley, Ph.D. Professor of Anatomy and NeurologyMechanisms underlying the specification, regulation, and neurodegeneration of dopaminergic and glutamatergic systems. |
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| David M. Ornitz, M.D., Ph.D. Alumni Endowed Professor and Interim Chair of Developmental BiologyFGFs in lung, skeletal, cardiovascular and CNS development and function |
| | Rohit V. Pappu, Ph.D. Associate Professor of Biomedical EngineeringAlzheimer’s disease; biophysics; mathematical modeling; thermodynamics |
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| Alexander Parsadanian, Ph.D. Research Assistant Professor of NeurologyRole of neurotrophic factors on different aspects of motor neuron neurobiology |
| | Joel S. Perlmutter, M.D. Elliot H. Stein Professor of Neurology; Professor of Radiology and Anatomy & Neurobiology; Head of the Movement Disorders SectionPharmacology, physiology and pathophysiology of basal ganglia and movement disorders. |
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| Alan Pestronk, M.D. Professor of Neurology and Pathology; Director of the Neuromuscular DivisionDiagnosis, pathogenesis and treatment of immune, hereditary and degenerative neuromuscular disorders |
| | David R. Piwnica-Worms, M.D., Ph.D. Professor of Radiology and Developmental BiologyMolecular imaging of gene expression and protein function in vivo; multidrug resistance transporters; metallopharmaceuticals |
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| Shelly E. Sakiyama-Elbert, Ph.D. Joseph and Florence Farrow Associate Professor of Biomedical EngineeringTissue and cellular engineering approaches to neurological diseases |
| | Mark S. Sands, Ph.D. Associate Professor of Internal Medicine and GeneticsPathophysiology and novel therapies for lysosomal storage diseases |
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| Anneliese M. Schaefer, J.D., Ph.D. Research Assistant Professor of Neurology; Deputy Director of the Hope Center for Neurological DisordersPathological changes of axons, motor units, and neuromuscular junctions in motor neuron disease |
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| Robert E. Schmidt, M.D., Ph.D. Professor of Pathology & Immunology; Director, Neuropathology DivisionPathogenetic mechanisms of diabetic and age-related autonomic neuropathy |
| | Christian T. Sheline, Ph.D. Research Assistant Professor of NeurologyMechanisms of zinc-mediated toxicity in neurodegeneration, injury and disease |
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| B. Joy Snider, M.D., Ph.D. Assistant Professor of NeurologyMechanisms of protein degradation and intracellular calcium homeostasis in neurodegenerative disorders |
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| Paul H. Taghert, Ph.D Professor of Anatomy & NeurobiologyCircadian neurobiology and developmental neurobiology |
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| | Conrad Chris Weihl, M.D., Ph.D. Assistant Professor of NeurologyProtein degradation pathways and their relation to aging, muscle weakness, and neurodegeneration |
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| Michael Wong, M.D., Ph.D. Assistant Professor of Neurology and PediatricsCellular mechanisms of epileptogenesis and seizure-induced brain injury |
| | David F. Wozniak, Ph.D. Research Professor of PsychiatryRole of NMDA receptors in neuropathologic changes and cognitive decline |
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| Kelvin A. Yamada, M.D. Associate Professor of Neurology and PediatricsModulation and derangements of synaptic transmission at central nervous system synapses |
| | Gregory J. Zipfel, M.D. Assistant Professor of Neurological Surgery and NeurologyRole of amyloid-β peptide and cerebral amyloid angiopathy in neurovascular dysfunction, ischemic brain injury and subarachnoid hemorrhage |
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| Charles F. Zorumski, M.D. Samuel B. Guze Professor and Head of Psychiatry; Professor of Anatomy & NeurobiologySynaptic development and plasticity related to neural injury |
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